Ashwagandha shows remarkable promise for increasing brain function. It has been used in India for people with mental deficits in geriatric patients, including amnesia. Researchers have found that ashwagandha can increase acetylcholine receptor activity. Increased acetylcholine receptor capacity might partly explain the cognition-enhancing and memory-improving effects of extracts from ashwagandha observed in animals and humans. Further studies indicate that ashwagandha stimulates the growth of axons and dendrites.
According to scientists, Ashwagandha most likely affects multiple body systems to promote emotional well-being, mental sharpness and physical endurance. Pharmacological studies indicate the mechanism of action is Withaferin-A, a primary Withanolide in Ashwagandha, which stimulates neurotransmitter pathways in the brain. This effect enhances memory and other
cognitive processes. Scientists have yet to pinpoint the specific functions supporting immune system response and other regulatory body systems, though it is believed that all the active glycowithanolides that derive from the plant
work together to alleviate anxiety and panic, mild mood swings, lack of mental clarity/focus and mental/physical fatigue.
Research has also found that raw ashwagandha increases the levels of three naturally powerful antioxidants: superoxide dismutase, catalase, and glutathione peroxidase. The effects of these antioxidants may explain the reported anti-stress, cognition-facilitating, anti-inflammatory and anti-aging effects produced in experimental animal and in clinical situations.
These findings are consistent with the therapeutic use of ashwagandha root in Ayurveda as an overall health promoter. The root is primarily recognized for its adaptogenic properties. An adaptogen is a physiological agent with the ability to naturally increase the body's resistance to emotional and physical stresses. Ayurvedic practitioners traditionally use Ashwagandha to promote gentle relaxation, emotional balance, and sexual vitality
Some possible benefits of our raw organic Ashwagandha root powder may include:
● Improving memory & mental function
● Benefits for occasional panic attacks & anxiety
● Battling depression & stabilizing mild to moderate mood changes
● Combating mental or physical fatigue
● Enhancing immune-system support
Suggested Use: 2 teaspoons daily.
Botanical Name: Withania Somnifera
Other Names: Winter Cherry, Indian Ginseng, Indian Winter Cherry
Ingredients: Raw Organic Ashwagandha Root Powder.
Origin: India - Certified Organic
Warning: Not to be used during pregnancy.
Z Natural Foods strives to offer the highest quality organically grown, raw, vegan, gluten free, non-GMO products available and exclusively uses low temperature drying techniques to preserve all the vital enzymes and nutrients. Our raw Ashwagandha Root powder is certified organic and passes our strict quality assurance which includes testing for botanical identity, heavy metals, chemicals and microbiological contaminants. ZNaturalFoods.com offers raw Organic Ashwagandha Root powder packaged in airtight stand-up, resealable foil pouches for optimum freshness. Once opened, just push the air out of the pouch before resealing it in order to preserve maximum potency. Keep your Organic raw Ashwagandha Root powder in a cool, dark, dry place.
1. Archana R, Namasivayam A. Antistressor effect of Withania somnifera. Journal of Ethnopharmacology. 1999;64:91-93.
2. Agarwal R, Diwanay S, Patki P, Patwardhan B. Studies on immunomodulatory activity of Withania somnifera (Ashwagandha) extracts in experimental immune inflammation. Journal of Ethnopharmacology. 1999;67:27-35.
3. Bhargava HN. Opioid peptides, receptors and immune functions. Drugs Abuse Res. (monograph), USA. 1990;86:220-3.
4. Bhattacharya SK, Goel RK, Kaur R, Ghosal S. Anti-stress activity of Sitoindosides VII and VIII, new Acylsterylglucosides from Withania Somnifera. Phytotherapy Research. 1987;1(1):32-7.
5. Bhattacharya S, Kumar A. Effects of glycowithanolides from Withania somnifera on an animal model of Alzheimer’s disease and perturbed central cholinergic markers of cognition in rats. Phytotherapy Research. 1995;9:110-113.
6. Bhattacharya A, Ramanathan M, Ghosal S, Bhattacharya SK. Effect of Withania somnifera glycowithanolides on iron-induced hepatotoxicity in rats. Phytotherapy Research. 2000;14:568-570.
7. Bhattacharya SK, Satyan KS, Ghosal S. Antioxidant activity of glycowithanolides from Withania somnifera. Indian Journal of Experimental Biology. 1997;35:236-239.
8. Chauhan RS. Effect of immuplus on humoral and cell mediated immunity in dogs. J. Immunol. Immunopathol. 1999;1:54-57.
9. Chattopadhyay S, Chaudhury S, Ghosal S. Activation of peritoneal macrophages by sitoindosides. Planta Med. 1987;54:16-9.
10. Dallman M, la Fleur S, Pecoraro N, Gomex F, Houshyar H, Akana S. Minireview: Glucocorticoids-Food Intake, Abdominal Obesity, and Wealthy Nations in 2004. Endocrinology Vol. 145, No.6 2633-2638.
11. Davis L, Kuttan G. Immunomodulatory activity of Withania somnifera. Journal of Ethnopharmacology. 2000;71:193-200.
12. Ehrke N, Mihich E. Effects of anticancer agents on immune responses. TIPS. 1985:412-417.
Dhuley JN. Effect of Ashwagandha on lipid peroxidation in stress-induced animals. Journal of Ethnopharmacology. 1998;60:173-8.
13. Ghosal S. Natural products with immunological effects. Indian J Indg Med. 1991;12:1-7.
Ghosal S, Lal J, Srivastava R et al. Immunomodulatory and CNS effects of Sitoindosides IX and X, two new glycowithanolides from Withania somnifera. Phytotherapy Research. 1989;3(5):201-6.
14. Grandhi A, Mujumdar AM, Patwardhan B. A comparative pharmacological investigation of Ashwagandha and Ginseng. Journal of Ethnopharmacology. 1994;44:131-5.
15. Hjemdahl P. Editorial: Stress and the Metabolic Syndrome An Interesting but Enigmatic Association Circulation 2002;106:2634.
16. Jankovic BD. Neural tissue hypersensitivity in psychiatric disorders with immunological features. J Immunol. 1985;135:853S-857S.
17. Karnick C.R., A double-blind, placebo-controlled clinical studies on the effects of Withania somnifera and Panax Ginseng Extracts on psychomotor performance in healthy Indian volunteers. Indian Medicine Vol. 3 No. 2,3, April-July 1991.
18. Kulkarni SK, Sharma A, Verma A, Ticku MK. Gaba receptor mediated anticonvulsant action of Withania somnifera Root extract. Indian Drugs. 1993;7(30):305-312.
19. Kuppurajan K, Rajogopalan SS, Sitaraman R, et al. Effect of Ashwagandha (Withania somnifera) on the process of ageing in human volunteers. Journal of Research in Ayurveda and Siddha. 1980;1(2):247-58.
20. LaValle J. Stress: The Hidden Factor for Weight Gain Nutrition Science News April 2001.
21. Mishra LC, Singh B, Dagenais S. Scientific basis for the therapeutic use of Withania somnifera (Ashwagandha): a review. Alternative Medicine Review. 2000;5(4):334-346.
22. Mukhopadhaya B, Chokrabarti A, Ghosal S, Bhattacharya SK. Immunomodulatory properties of some Indian medicinal plants. In Emerging Drugs Volume 1, Molecular Aspects of Asian Medicines, Eds.
23. Akitane Mori, M.D., Ph.D., Tetsuo Satoh, Ph.D., PJD Publications Ltd. (Westbury, NY) 2001.
24. Naidu P, Singh A, Kulkarni S. Effect of Withania somnifera root extract on haloperidol-induced orofacial dyskinesia: possible mechanisms of action. Journal of Medicinal Food. 2003;6(2):107-114.
25. Pallabi DE, Dasgupta SC, Gomes A. Immunopotentiating and immunoprophylactic activities of Immune 21, a polyherbal product. Indian Journal of Pharmacology. 1998;30:163-8.
26. Prabhu M., Rao A., Karanth K.S. Neuropharmacological Activity of Withania somnifera Fitoterapia Volume LXL, No. 3, 1990.
27. Ramarao P, Rao KT, Srivastava RS, Ghosal S. Effects of glycowithanolides from Withania somnifera on morphine-induced inhibition of intestinal motility and tolerance to analgesia in mice. Phytotherapy Research. 1995;9:66-68.
28. Rosmond R. Stress induced disturbances of the HPA axis: a pathway to Type 2 diabetes? Med Sci Monit, 2003;9(2):RA35-39.
29. Rosmond R, Dallman M, Bjorntorp P. Stress-Related Cortisol Secretion in Men:Relationship with Abdominal Obesity and Endocrine, Metabolic and Hemodynamic Abnormalities The Journal of Clinical Endocrinology & Metabolism Vol. 83, No.6 1853-1859.
30. Fruehwald-Schultes B, Kern W, Bong W, Wellhoener P, Kerner W, Born J, Fehm H, Peters A. Supraphysiological Hyperinsulinemia Acutely Increases Hypothalamic-Pituitary-Adrenal Secretory Activity in Humans. The Journal of Clinical Endocrinology & Metabolism Vol. 84, No. 9 3041-3046.
31. Selye H. The evolution of stress concept. Am Scientist. 1973;61:692-698.
32. Shah LP, Patil SP, Patil J. Observations on clinical evaluation of indigenous herbal drugs in the treatment of mental illnesses. Indian Journal of Pharmacology. 1997;29:S347-S349.
33. Shukla SD, Jain S, Sharma K, Bhatnagar M. Stress induced neuron degeneration and protective effects of Semecarpus anacardium Linn. and Withania somnifera Dunn. in hippocampus of albino rats: an ultrastructural study. Indian Journal of Experimental Biology. 2000;38:1007-1013.
34. Singh A, Saxena E, Bhutani KK. Adrenocorticosterone alterations in male, albino mice treated with Trichopus zeylanicus, Withania somnifera and Panax ginseng preparations. Phytotherapy Research. 2000;14:122-125.
35. Tongia SK, Bose S, Jain HL. Cytoprotective and efficiency optimizing effect of Eumil against routine mental & physical stress in bank clerks and gymnast-body builders. Indian J Indg Med. 1995-96;17(2):13-24.
36. Vaidya ADB. The status and scope of Indian medicinal plants acting on central nervous system. Indian Journal of Pharmacology. 1997;29:S340-S343.
37. Vicennati V, Pasquali R Abnormalities of the Hypothalamic-Pituitary-Adrenal Axis in Nondepressed Women with Abdominal Obesity and Relations with Insulin Resistance: Evidence for a Central and a Peripheral Alteration. The Journal of Clinical Endocrinology & Metabolism Vol. 85, No. 11 4093-4098.
38. Ziauddin M, Phansalkar N, et al. Studies on the immunomodulatory effects of Ashwagandha. Journal of Ethnopharmacology. 1996;50:69-76.