Gotu Kola (non-GMO) has been traditionally used as a remedy for countless ailments. It has been used extensively over several thousand years in remedies supporting a multitude of different areas of health and wellbeing. Herbalists and natural medicine practitioners strongly believe that Gotu Kola may possibly have has several powerful qualities. Many of them uphold that the Gotu Kola herb has properties that support a healthy immune system.
Some traditional claims that have not been validated by science is that women have used Gotu Kola for the purposes of birth control, and some herb specialists have established that Gotu Kola is an antidote for poison mushrooms and arsenic poisoning. They also claim that Gotu Kola preparations can be used to treat snakebites, herpes, fractures, and sprains.
Recently Gotu Kola has gained popularity as a natural remedy for the supporting skin and connective tissue healing problems such as scleroderma, psoriatic arthritis (arthritis occurring in conjunction with psoriasis), ankylosing spondylitis (arthritis of the spine), and rheumatoid arthritis. Gotu Kola is also said to support the brain, nervous system and vein health.
More recent studies confirm many of Gotu Kola's traditional uses and also suggest possible new applications for Gotu Kola, such as supporting healthy circulation and blood vessel health thereby possibly boosting memory and intelligence, easing anxiety and speeding the healing of wounds and burns.
Supporting the nervous system may be necessary when one has a predisposition to stress related problems. Gotu Kola has shown some extremely remarkable potential. Scientists have established that compounds in Gotu Kola known as triterpene acids may in fact bind to receptors in your central nervous system and reduce your startle response.
One of the many possible benefits of Gotu Kola may include its effectiveness in supporting the overall health of skin like cellulite and keloids. The hardening of connective tissue cells below the skins surface causes cellulite and Gotu Kola shows potential in possibly slowing down this process.
Some possible traditional uses of Raw Organic Gotu Kola Leaf Powder may include:
● May support glandular health
● Supporting the nervous system
● May support the healing process of wounds & burns
● May support the healing of connective tissue & skin
● May relieve physical & mental exhaustion
● May support stress related problems
● Supporting healthy brain function
● May reduce blood pressure
● Supports a healthy inflammation response
● May support the nervous system
● Reducing venous insufficiency
● Supporting vein health
Suggested Use: Mix 1 teaspoon with juice, yogurt, or add to your favorite smoothie.
Botanical Name: Centella Asiatica
Other Names: Indian Pennywort, Marsh Penny, Spadeleaf, Tiger's Herb, Brahmi, and Pennywort.
Ingredients: Raw Organic Gotu Kola Leaf Powder.
Origin: Sri Lanka - Certified Organic
Z Natural Foods strives to offer the highest quality organically grown, raw, vegan, gluten free, non-GMO products available and exclusively uses low temperature drying techniques to preserve all the vital enzymes and nutrients. Our Raw Gotu Kola Leaf Powder is certified organic and passes our strict quality assurance which includes testing for botanical identity, heavy metals, chemicals and microbiological contaminants. ZNaturalFoods.com offers Raw Organic Gotu Kola Leaf Powder packaged in airtight stand-up, resealable foil pouches for optimum freshness. Once opened, just push the air out of the pouch before resealing it in order to preserve maximum potency. Keep your Raw Organic Gotu Kola Leaf Powder in a cool, dark, dry place.
1. Pittella, Frederico, et al. Int J Mol Sci. 10(9): Antioxidant and Cytotoxic Activities of Centella asiatica (L) Urb. PubMed: U.S. National Library of Medicine and the National Institutes of Health. [Online] September 2009. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2769141/?tool=pubmed. DOI 10.3390/ijms10093713.
2. Apichartsrangkoon, A., Wongfhun, P. and Gordon, M.H. J Food Sci. 74(9): Flavor characterization of sugar-added pennywort (Centella asiatica L.) juices treated with ultra-high pressure and thermal processes. PubMed: U.S. National Library of Medicine and the National Institutes of Health. [Online] Nov-Dec 2009. http://www.ncbi.nlm.nih.gov/pubmed/20492095.
3. Halpern, Georges M. and Weverka, Peter. The Healing Trail: Essential Oils of Madagascar. s.l.: Basic Health Publications, Inc., 2003. ISBN 1591200164, 9781591200161.
4. Bagavan, A., et al. Vet Parasitol. 166(3-4): Adulticidal and larvicidal efficacy of some medicinal plant extracts against tick, fluke and mosquitoes. PubMed: U.S. National Library of Medicine and the National Institutes of HealthM. [Online] December 23, 2009. http://www.ncbi.nlm.nih.gov/pubmed/19819626.
5. Haftek, M., et al. Exp Dermatol. 17(11): Clinical, biometric and structural evaluation of the long-term effects of a topical treatment with ascorbic acid and madecassoside in photoaged human skin. PubMed: U.S. National Library of Medicine and the National Institutes of Health. [Online] November 2008. http://www.ncbi.nlm.nih.gov/pubmed/18503551.
6. Mato, Lugkana, et al. Centella asiatica Improves Physical Performance and Health-related Quality of Life in Healthy Elderly Volunteer. Oxford University Press: Evidenced-based Complementary and Alternative Medicine. [Online] October 30, 2009. http://www.ncbi.nlm.nih.gov/pubmed/19880441. DOI 10.1093/ecam/nep177.
7. Rao, K. G. Mohandas, Rao, S. Muddanna and Rao, S. Gurumadhva. Evid Based Complement Alternat Med. 6(2): Enhancement of Amygdaloid Neuronal Dendritic Arborization by Fresh Leaf Juice of Centella asiatica (Linn) During Growth Spurt Period in Rats. PubMed: U.S. National Library of Medicine and the National Institutes of Health. [Online] June 2009. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2686623/?tool=pubmed. DOI 10.1093/ecam/nem079.
8. Awad, R., et al. Can J Physiol Pharmacol 85(9): Effects of traditionally used anxiolytic botanicals on enzymes of the gamma-aminobutyric acid (GABA) system. MD Consult. [Online] September 1, 2007. http://www.mdconsult.com/das/citation/body/205390697-4/jorg=journal&source=MI&sp=20220147&sid=1012343295/N/20220147/1.html?issn=0008-4212#bib. DOI 10.1139/Y07-083.
9. Kaziulin, A.N., Petukhov, A.B. and Kucheriavy?, IuA. Vopr Pitan. 75(2): Efficiency of includes of bioactive substances in diet of patient with hepatic encephalopathy. PubMed: U.S. National Library of Medicine and the National Institutes of Health. [Online] 2006. http://www.ncbi.nlm.nih.gov/pubmed/16729760.
10. Visweswari, G., et al. Epilepsy Behav. 17(3): Evaluation of the anticonvulsant effect of Centella asiatica (gotu kola) in pentylenetetrazol-induced seizures with respect to cholinergic neurotransmission. PubMed: U.S. National Library of Medicine and the National Institutes of Health; Elsevier Inc. [Online] March 2010. http://www.ncbi.nlm.nih.gov/pubmed/20144879.
11. Haleagrahara, Nagaraja and Ponnusamy, Kumar. Neuroprotective effect of Centella asiatica extract (CAE) on experimentally induced parkinsonism in aged Sprague-Dawley rats. The Journal of Toxicological Sciences 35(1). [Online] February 2010. http://www.jstage.jst.go.jp/article/jts/35/1/35_41/_article. DOI 10.2131/jts.35.41.
12. Krishnamurthy, R.G., et al. J Neurosci Res. 87(11): Asiatic acid, a pentacyclic triterpene from Centella asiatica, is neuroprotective in a mouse model of focal cerebral ischemia. PubMed: U.S. National Library of Medicine and the National Institutes of Health. [Online] August 15, 2009. http://www.ncbi.nlm.nih.gov/pubmed/19382233.
13. Gnanapragasam, A., et al. Mol Cell Biochem. 294(1-2): Adriamycin induced myocardial failure in rats: protective role of Centella asiatica. PubMed: U.S. National Library of Medicine and the National Institutes of Health. [Online] January 2007. http://www.ncbi.nlm.nih.gov/pubmed/16786185.
14. Sharma, R. and Sharma, J. Phytother Res. 19(7): Modification of gamma ray induced changes in the mouse hepatocytes by Centella asiatica extract: in vivo studies. PubMed: U.S. National Library of Medicine and the National Institutes of Health. [Online] July 2005. http://www.ncbi.nlm.nih.gov/pubmed/16161023.
15. Cesarone, M.R., et al. Angiology. 52 (Suppl 2): Evaluation of treatment of diabetic microangiopathy with total triterpenic fraction of Centella asiatica: a clinical prospective randomized trial with a microcirculatory model.PubMed: U.S. National Library of Medicine and the National Institutes of Health. [Online] October 2001. http://www.ncbi.nlm.nih.gov/pubmed/11666124.
16. Bian, Guang-Xing, et al. Biological & Pharmaceutical Bulletin 31(3): Madecassoside Reduces Ischemia-Reperfusion Injury on Regional Ischemia Induced Heart Infarction in Rat. J-STAGE: The Pharmaceutical Society of Japan. [Online] 2008. http://www.jstage.jst.go.jp/article/bpb/31/3/31_458/_article. DOI 0.1248/bpb.31.458.
17. Incandela, L., et al. Angiology. 52 (Suppl 2): Total triterpenic fraction of Centella asiatica in the treatment of venous hypertension: a clinical, prospective, randomized trial using a combined microcirculatory model. PubMed: U.S. National Library of Medicine and the National Institutes of Health. [Online] October 2001. http://www.ncbi.nlm.nih.gov/pubmed/11666126.
18. Hussin, M., et al. J Food Sci. 74(2): Modulation of lipid metabolism by Centella asiatica in oxidative stress rats. PubMed: U.S. National Library of Medicine and the National Institutes of Health. [Online] March 2009. http://www.ncbi.nlm.nih.gov/pubmed/19323754.
19. Qinna, N., et al. Int J Impot Res. 21(5): A new herbal combination, Etana, for enhancing erectile function: an efficacy and safety study in animals. PubMed: U.S. National Library of Medicine and the National Institutes of Health. [Online] Sep-Oct 2009. http://www.ncbi.nlm.nih.gov/pubmed/19494825.
20. Muller, Daniel and Selfridge, Nancy J. chapter 46 - Fibromyalgia Syndrome. [book auth.] David Rakel. Integrative Medicine. Philadelphia, PA: Saunders, an imprint of Elsevier Inc., 2007. ISBN-13: 978-1-4160-2954-0; ISBN-10: 1-4160-2954-0.
21. Guo, J.S., Cheng, C.L. and Koo, M.W. Planta Med. 70(12): Inhibitory effects of Centella asiatica water extract and asiaticoside on inducible nitric oxide synthase during gastric ulcer healing in rats. PubMed: U.S. National Library of Medicine and the National Institutes of Health. [Online] December 2004. http://www.ncbi.nlm.nih.gov/pubmed/15643549.
22. Sastravaha, G., et al. J Int Acad Periodontol. 7(3): Adjunctive periodontal treatment with Centella asiatica and Punica granatum extracts in supportive periodontal therapy. PubMed: U.S. National Library of Medicine and the National Institutes of Health. [Online] July 2005. http://www.ncbi.nlm.nih.gov/pubmed/16022023.
23. di Paola, R., et al. 3,5-Dicaee Radic Res. 44(1): 4-malonylquinic acid reduced oxidative stress and inflammation in a experimental model of inflammatory bowel disease. PubMed: U.S. National Library of Medicine and the National Institutes of Health. [Online] January 2010. http://www.ncbi.nlm.nih.gov/pubmed/19886745.
24. Zieve, David, Juhn, Greg and Eltz, David R. Gotu kola. University of Maryland Medical Center Medical Reference: Complementary Medicine. [Online] October 15, 2009. http://www.umm.edu/altmed/articles/gotu-kola-000253.htm.
25. Zhang, L., et al. Phytomedicine: Protective effects of Asiaticoside on acute liver injury induced by lipopolysaccharide/D-galactosamine in mice. PubMed: U.S. National Library of Medicine and the National Institutes of Health; Elsevier GmbH. [Online] February 17, 2010. http://www.ncbi.nlm.nih.gov/pubmed/20171071.
26. Zhang, L.N., et al. Exp Toxicol Pathol.: Protective effects of asiaticoside on septic lung injury in mice. PubMed: U.S. National Library of Medicine and the National Institutes of Health; Elsevier GmbH. [Online] May 12, 2010. http://www.ncbi.nlm.nih.gov/pubmed/20471230.
27. Liu, M., et al. Int Immunopharmacol. 8(11): Anti-rheumatoid arthritic effect of madecassoside on type II collagen-induced arthritis in mice. PubMed: U.S. National Library of Medicine and the National Institutes of Health. [Online] November 2008. http://www.ncbi.nlm.nih.gov/pubmed/18652917.
28. Hong, S.S., et al. Arch Pharm Res. 28(4): Advanced formulation and pharmacological activity of hydrogel of the titrated extract of C. asiatica. PubMed: U.S. National Library of Medicine and the National Institutes of Health. [Online] April 2005. http://www.ncbi.nlm.nih.gov/pubmed/15918527.
29. Klövekorn, W., Tepe, A. and Danesch, U. Int J Clin Pharmacol Ther. 45(11): A randomized, double-blind, vehicle-controlled, half-side comparison with a herbal ointment containing Mahonia aquifolium, Viola tricolor and Centella asiatica for the treatment of mild-to-moderate atopic dermatitis. PubMed: U.S. National Library of Medicine and the National Institutes of Health. [Online] November 2007. http://www.ncbi.nlm.nih.gov/pubmed/18077922.
30. Draelos, Z.D., et al. Skinmed. 8(2): Evaluation of an onion extract, Centella asiatica, and hyaluronic acid cream in the appearance of striae rubra. PubMed: U.S. National Library of Medicine and the National Institutes of Health. [Online] Mar-Apr 2010. http://www.ncbi.nlm.nih.gov/pubmed/20527138.
31. Salas Campos, L., Fernándes Mansilla, M. and Martínez de la Chica, A.M. Rev Enferm. 28(5): Topical chemotherapy for the treatment of burn. PubMed: U.S. National Library of Medicine and the National Institutes of Health. [Online] May 2005. http://www.ncbi.nlm.nih.gov/pubmed/15981974.
32. Tholon, L., et al. J Cosmet Sci. 53(4): An in vitro, ex vivo, and in vivo demonstration of the lipolytic effect of slimming liposomes: An unexpected alpha(2)-adrenergic antagonism. PubMed: U.S. National Library of Medicine and the National Institutes of Health. [Online] Jul-Aug 2002. http://www.ncbi.nlm.nih.gov/pubmed/12219247.
33. Venardos, Kylie M., Kaye, David M. Current Medicinal Chemistry 14(14): Myocardial Ischemia-Reperfusion Injury, Antioxidant Enzyme Systems, and Selenium: A Review. IngentaConnect. [Online] June 2007. http://www.ingentaconnect.com/content/ben/cmc/2007/00000014/00000014/art00005. DOI 10.2174/092986707780831078.
34. Ivanov, V., Ivanova, S., Kalinovsky, T., Niedzwiecki, A., Rath, M. J Cardiovasc Pharmacol. 52(1): Plant-derived micronutrients suppress monocyte adhesion to cultured human aortic endothelial cell layer by modulating its extracellular matrix composition. Medscape: Medline Abstract. [Online] 2008. http://www.medscape.com/medline/abstract/18594473.
35. Capasso, Francesco. Phytotherapy: a quick reference to herbal medicine. s.l.: Springer, 2003. ISBN 3540000526, 9783540000525.
36. Gnanapragasam, A., et al. Life Sciences 76(5): Protective effect of Centella asiatica on antioxidant tissue defense system against adriamycin induced cardiomyopathy in rats. ScienceDirect. [Online] December 17, 2004. http://dx.doi.org/10.1016/j.lfs.2004.09.009.
37. Eberhardt, Robert T. and Raffetto, Joseph D. Circulation 111: Chronic Venous Insufficiency. American Heart Association, Inc. [Online] 2005.http://circ.ahajournals.org/cgi/content/full/111/18/2398.
38. Barclay, Laurie. A Scientific Solution to Unsightly Cellulite. Life Extension Magazine. [Online] August 2008. http://www.lef.org/magazine/mag2008/aug2008_A-Scientific-Solution-to-Unsightly-Cellulite_01.htm.
39. Thorne Research, Inc. Monograph: Centella asiatica Monograph. Alternative Medicine Review 12(1). [Online] March 2007. http://www.thorne.com/media/alternative_medicine_review/2007/Volume_12/Number_1/Centella-asiatica-mono.pdf.
40. Stargrove, Mitchell Bebel, Treasure, Jonathan and McKee, Dwight L. Herb, Nutrient, and Drug Interactions. s.l.: Elsevier Health Sciences, 2008. ISBN 0323029647, 9780323029643.
41. Incandela, L., et al. Angiology. 52(Suppl 2): Modification of the echogenicity of femoral plaques after treatment with total triterpenic fraction of Centella asiatica: a prospective, randomized, placebo-controlled trial. PubMed: U.S. National Library of Medicine and the National Institutes of Health. [Online] October 2001. http://www.ncbi.nlm.nih.gov/pubmed/11666127.
42. International Diabetes Federation. How does Diabetes Lead to Cardiovascular Disease? International Diabetes Federation. [Online] 2005. http://www.cvd.idf.org/Double_Jeopardy/How_does_Diabetes_Lead_to_CVD_/index.html.
43. Duke, James A. The Green Pharmacy Herbal Handbook: Your Everyday Reference to the Best Herbs for Healing. 2002: Macmillan. ISBN 0312981511, 9780312981518.
44. Murad, Howard. The Cellulite Solution: A Doctor's Program for Losing Lumps, Bumps, Dimples, and Stretch Marks. s.l.: Macmillan, 2006. ISBN 0312334621, 9780312334628.
45. Barel, Andre O., Paye, Marc and Maibach, Howard I. Handbook of Cosmetic Science and Technology, Third Edition. 2009: Informa Health Care. ISBN 1420069632, 9781420069631.
46. Goldman, Mitchel P., Bacci, Pier Antonio and Leibaschoff, Gustavo. Cellulite: pathophysiology and treatment. s.l.: Marcel Dekker, 2006. ISBN 0824729854, 9780824729851.
47. Baran, Robert and Maibach, Howard I. Textbook of cosmetic dermatology. s.l.: Taylor & Francis, 2004. ISBN 1841843113, 9781841843117.
48. Khan, Misbah H., et al. Journal of the American Academy of Dermatology 62(3): Treatment of cellulite Part I. Pathophysiology. MD Consult. [Online] March 2010. http://www.mdconsult.com/das/article/body/202578781-3/jorg=journal&source=MI&sp=22941240&sid=1003163609/N/735326/1.html?issn=0190-9622.
49. Rawlings, A. V. International Journal of Cosmetic Science 28: Cellulite and its treatment. Society of Cosmetic Scientists and the Socie´te´ Franc¸aise de Cosme´tologie. [Online] 2006. http://assets0.pubget.com/pdf/18489274.pdf.
50. Catania 42(370): Efficacy of Melilotus officinalis (L.) Pallas in cellulitis treatment. Bollettino Accademia Gioenia Sci. Nat. [Online] 2009. .
51. Thomson, Graeme E. The Health Benefits of Traditional Chinese Plant Medicines: Weighing the scientific evidence. Australian Government: Rural Industries Research and Development Corporation. [Online] February 2007. https://rirdc.infoservices.com.au/downloads/06-128.pdf.
52. Yendo, A.C., et al. Mol Biotechnol.: Production of Plant Bioactive Triterpenoid Saponins: Elicitation Strategies and Target Genes to Improve Yields. PubMed: U.S. National Library of Medicine and the National Institutes of Health. [Online] March 4, 2010. http://www.ncbi.nlm.nih.gov/pubmed/20204713.
53. Coldren, Christopher D., et al. Planta Med 69(8): Gene Expression Changes in the Human Fibroblast Induced by Centella asiatica Triterpenoids. Thieme eJournals. [Online] 2003. https://www.thieme-connect.com/ejournals/abstract/plantamedica/doi/10.1055/s-2003-42791. DOI 10.1055/s-2003-42791.
54. Dweck, Anthony C. Natural Ingredients Used in Cosmeceuticals. [book auth.] Kenneth A. Walters and Michael S. Roberts. Dermatologic, Cosmeceutic, and Cosmetic Development: Therapeutic and Novel Approaches. s.l.: CRC Press, 2007.
55. Barclay, Laurie. Medscape Medical News: Management of Venous Ulcers Reviewed. Medscape Today. [Online] April 29, 2010. http://www.medscape.com/viewarticle/720987.
56. Chiummariello, S., et al. G Chir. 30(11-12): Multicentric study on a topical compound with lymph-draining action in the treatment of the phlebostatic ulcer of the inferior limbs. PubMed: U.S. National Library of Medicine and the National Institutes of Health. [Online] Nov-Dec 2009. http://www.ncbi.nlm.nih.gov/pubmed/20109380.
57. Sy, G.Y., et al. Dakar Med. 50(2): Healing activity of methanolic extract of the barks of Spathodea campanulata Beauv (Bignoniaceae) in rat experimental burn model. PubMed: U.S. National Library of Medicine and the National Institutes of Health. [Online] 2005. http://www.ncbi.nlm.nih.gov/pubmed/16295762.
58. Healthwise. Skin Problems & Treatments Health Center: Varicose Veins - Topic Overview. WebMD. [Online] February 11, 2008. http://www.webmd.com/skin-problems-and-treatments/tc/varicose-veins-topic-overview.
59. Levine, Norman. Skin Problems & Treatments Health Center: Your Skin and Stretch Marks. WebMD. [Online] February 28, 2008. http://www.webmd.com/skin-problems-and-treatments/stretch-marks.
60. Leibaschoff, Gustavo. Medical Treatment of Cellulite. [book auth.] Mitchel P. Goldman, Pier Antonio Bacci and Gustavo Leibaschoff. Cellulite: pathophysiology and treatment. s.l.: Marcel Dekker, 2006, Vol. Volume 37 of Basic and clinical dermatology. ISBN 0824729854, 9780824729851.