Native to China, Shiitake mushrooms (non-GMO) have been eaten for nearly 6000 years. The mushrooms gained prominence during the Ming Dynasty (1368-1644), where they were considered the "elixir of life" and reserved to be enjoyed only by the emperor and his family. Aside from being a rich source of protein, shiitake mushrooms supply niacin, riboflavin, thiamin, potassium and iron, and are a good source of vitamins A, B and C. When used in their sun-dried form they provide a valuable dose of Vitamin D, found in very few foods. They contain more than 50 different enzymes, including pepsin that supports digestion and asparaginase, which is a substance that supports a healthy immune response.
Recent studies have traced shiitakes' legendary benefits to an active compound contained in these mushrooms called lentinan. Among lentinan’s supportive benefits is its, ability to support the immune system, strengthening the body’s ability to fight infection and disease. Against influenza and other viruses, lentinan has been shown to be even very effective; it even may possibly improve the immune status of individuals infected with HIV, the virus that can cause AIDS.
A large number of animal studies conducted over the last ten years have shown that another active component in shiitake mushrooms called eritadenine may support healthy lipid levels. Even when lab animals are given dietary protein rich in methionine (an amino acid researchers have found causes an increase in cholesterol formation), eritadenine still lowers plasma cholesterol levels in a dose-dependent manner. In other words, the more eritadenine given, the better the support for healthy lipid levels are.
L-ergothioneine, a powerful antioxidant, has been discovered in mushrooms, thanks to a new analytical method capable of identifying this antioxidant in plant material. In research presented at the 2005 American Chemical Society meeting in Washington, D.C., an American research team revealed that mushrooms contain higher concentrations L-ergothioneine than either of the two dietary sources previously believed to contain the most: chicken liver and wheat germ.
Thrombosis, the formation of a blood clot that inhibits blood-flow, has been shown to be significantly reduced by individuals consuming shiitake mushroom oil. The Department of Agricultural and Biological Chemistry at Nihon University in Japan has demonstrated that the levels of lenthionine found in shiitake mushrooms may possibly inhibit platelet aggregation.
Some possible traditional uses of Raw Organic Shiitake Mushroom Powder may include:
● Containing more than 50 different enzymes
● May reduce cellular mutation by way of a branched beta-glucan called Lentinan
● Containing eritadenine which supports healthy cholesterol levels
● Supports a healthy immune system
● Good natural source of vitamin D
● Powerful antioxidant properties
● May reduce blood clots
Suggested Use: Add 1 - 2 teaspoons to dishes, sauces, smoothies or infuse in a tea.
Botanical Name: Lentinus edodes, Lentinula edodes
Other Names: Forest Mushroom, Chinese Mushroom, Black Mushroom, Lentinula, Pasania fungus, Hua Gu, Japanese mushroom, Black Forest mushroom, golden oak mushroom, oakwood mushroom
Ingredients: Organic Shiitake Mushroom Powder.
Origin: China - Certified Organic
Z Natural Foods strives to offer the highest quality organically grown, raw, vegan, gluten free, non-GMO products available and exclusively uses low temperature drying techniques to preserve all the vital enzymes and nutrients. Our Raw Organic Shiitake Mushroom Powder is organically grown in a traditional manner by Chinese herbalists. This products passes our strict quality assurance which includes testing for botanical identity, heavy metals, chemicals and microbiological contaminants. ZNaturalFoods.com offers Raw Organic Shiitake Mushroom Powder packaged in airtight stand-up, resealable foil pouches for optimum freshness. Once opened, just push the air out of the pouch before resealing it in order to preserve maximum potency. Keep your Organic Raw Shiitake Mushroom Powder in a cool, dark, dry place.
1. Bisen PS, Baghel RK, Sanodiya BS et al. Lentinus edodes: a macrofungus with pharmacological activities. Curr Med Chem. 2010;17(22):2419-30. Review. 2010.
2. Brauer D, Kimmons T, and Phillips M. Comparison of Two Methods for the Quantitation of B-Glucans from Shiitake Mushrooms. Journal of Herbs, Spices, & Medicinal Plants, Volume 13, Number 3 (January 2007), pp. 15-26. 2007.
3. Bruhn JN, Mihail JD, and Pickens JB. Forest farming of shiitake mushrooms: an integrated evaluation of management practices. Bioresour Technol. 2009 Dec;100(24):6472-80. Epub 2009 Jul 28. 2009.
4. Chan GCF, Chan WK, and Sze DMY. The effects of -glucan on human immune and cancer cells. Journal of Hematology & Oncology 2009, 2:25 (10 June 2009). 2009.
5. Chandra L, Alexander H, Traoré D et al. White button and shiitake mushrooms reduce the incidence and severity of collagen-induced arthritis in dilute brown non-agouti mice. J Nutr. 2011 Jan;141(1):131-6. Epub 2010 Nov 24. 2011.
6. Christopher L, Traore D, and Kuvibidla S. Consumption of diets fortified with edible mushrooms alters IL-6 secretion in vivo and in vitro and spleen cell proliferation in dextran sodium sulfate (DSS)-treated mice. FASEB J. April 2010, 24; (Meeting Abstract Supplement) lb390. 2010.
7. Driscoll M, Hansen R, Ding C et al. Therapeutic potential of various beta-glucan sources in conjunction with anti-tumor monoclonal antibody in cancer therapy. Cancer Biol Ther. 2009 Feb;8(3):218-25. Epub 2009 Feb 3. 2009.
8. Falandysz J. Selenium in edible mushrooms. J Environ Sci Health C Environ Carcinog Ecotoxicol Rev. 2008 Jul-Sep;26(3):256-99. 2008.
9. Fang N, Li Q, Yu S et al. Inhibition of Growth and Induction of Apoptosis in Human Cancer Cell Lines by an Ethyl Acetate Fraction from Shiitake Mushrooms. The Journal of Alternative & Complementary Medicine, Volume 12, Number 2 (March 2006), pp. 125-132. 2006.
10. Gold MA, Cernusca MM, and Godsey LD. A competitive market analysis of the United States shiitake mushroom marketplace. Hort Technology, July 2008; 18: 489 - 499. 2008.
11. Hearst R, Nelson D, McCollum G et al. An examination of antibacterial and antifungal properties of constituents of Shiitake (Lentinula edodes) and oyster (Pleurotus ostreatus) mushrooms. Complement Ther Clin Pract. 2009 Feb;15(1):5-7. Epub 2008 Dec 2. 2009.
12. Kojima H, Akaki J, Nakajima S et al. Structural analysis of glycogen-like polysaccharides having macrophage-activating activity in extracts of Lentinula edodes mycelia. J Nat Med. 2010 Jan;64(1):16-23. Epub 2009 Aug 27. 2010.
13. Kuvibidila S and French C. White button, shiitake, and portabella mushrooms inhibit the secretion of vascular endothelial growth factor (VEGF) and the proliferation of the androgen dependent LNCap prostate cancer cell line. FASEB J, Apr 2011; 25: 979.11. 2011.
14. Martin KR and Brophy SK. Commonly consumed and specialty dietary mushrooms reduce cellular proliferation in MCF-7 human breast cancer cells. Exp Biol Med (Maywood). 2010 Nov 1;235(11):1306-14. Epub 2010 Oct 4. 2010.
15. Ramberg JE, Nelson ED, and Sinnott RA. Immunomodulatory dietary polysaccharides: a systematic review of the literature. Nutrition Journal 2010, 9:54 (18 November 2010): 1-22. 2010.
16. Rao JR, Smyth TJ, Millar BC et al. Antimicrobial properties of shiitake mushrooms (Lentinula edodes). Int J Antimicrob Agents. 2009 Jun;33(6):591-2. Epub 2008 Dec 31. 2009.
17. Regula J, Krejpcio Z, and Staniek H. Bioavailability of iron from cereal products enriched with dried shittake mushrooms (Lentinula edodes) as determined by iron regeneration efficacy method in female rats. J Med Food. 2010 Oct;13(5):1189-94. 2010.
18. Rop O, Mlcek J, and Jurikova T. Beta-glucans in higher fungi and their health effects. Nutr Rev. 2009 Nov;67(11):624-31. Review. 2009.
19. Sasidharan S, Aravindran S, Latha LY et al. In vitro antioxidant activity and hepatoprotective effects of Lentinula edodes against paracetamol-induced hepatotoxicity. Molecules. 2010 Jun 23;15(6):4478-89. 2010.
20. Spierings EL, Fujii H, Sun B et al. A Phase I study of the safety of the nutritional supplement, active hexose correlated compound, AHCC, in healthy volunteers. J Nutr Sci Vitaminol (Tokyo). 2007 Dec;53(6):536-9. 2007.
21. Willcox DC, Willcox BJ, Todoriki H et al. . The Okinawan Diet: Health Implications of a Low-Calorie, Nutrient-Dense, Antioxidant-Rich Dietary Pattern Low in Glycemic Load. J. Am. Coll. Nutr., Aug 2009; 28: 500S - 516S. 2009.
22. Xu B and Chang K. Total phenolic, phenolic acid, anthocyanin, flavan-3-ol, and flavonol profiles and antioxidant properties of pinto and black beans (Phaseolus vulgaris L.) as affected by thermal processing. Journal of Agricultural and Food Chemistry, 2009; 57: 4754-4764. 2009.
23. Yarnell E and Abascal K. Holistic Approaches to Prostate Cancer. Alternative & Complementary Therapies, Volume 14, Number 4 (August 2008), pp. 164-180. 2008.
24. Shiitake Mushroom.
25. Stamets 2000, p. 260
26. Kazuko E. (2006). The Complete Book of Japanese Cooking. London, UK: Hermes House. p. 77. ISBN 978-0-681-28004-5.
27. Ciesla WM. (2002). Non-wood forest products from temperate broad-leaved trees. Food & Agriculture Org. p. 89. ISBN 92-5-104855-X.
28. Stamets 2000, p. 259
29. Neidleman SL. (1993). Advances in Applied Microbiology 39. Academic Press. p. 153. ISBN 0-12-002639-2.
30. Leatham, Gary F. (1982). "Cultivation of shiitake, the Japanese forest mushroom, on logs: a potential industry for the United States". Forest Prod. J. (Forest Products Research Society) 32 (8): 29–35.
31. Mushrooms and vitamin D
32. Lee GS, Byun HS, Yoon KH, Lee JS, Choi KC, Jeung EB (March 2009). "Dietary calcium and vitamin D2 supplementation with enhanced Lentinula edodes improves osteoporosis-like symptoms and induces duodenal and renal active calcium transport gene expression in mice". Eur J Nutr 48 (2): 75–83. doi:10.1007/s00394-008-0763-2. PMID 19093162.
33. Ko JA, Lee BH, Lee JS, Park HJ. (April 2008). "Effect of UV-B exposure on the concentration of vitamin D2 in sliced shiitake mushroom (Lentinus edodes) and white button mushroom (Agaricus bisporus).". J Agric Food Chem. 50 (10): 3671–3674. doi:10.1021/jf073398s.
34. Nakano H, Namatame K, Nemoto H, Motohashi H, Nishiyama K, Kumada K. (1999). "A multi-institutional prospective study of lentinan in advanced gastric cancer patients with unresectable and recurrent diseases: effect on prolongation of survival and improvement of quality of life. Kanagawa Lentinan Research Group". Hepato-gastroenterology 46 (28): 2662–8. PMID 10522061.
35. Oba K, Kobayashi M, Matsui T, Kodera Y, Sakamoto J. (2009). "Individual patient based meta-analysis of lentinan for unresectable/recurrent gastric cancer". Anticancer Research 29 (7): 2739–45. PMID 19596954.
36. Bisen PS, Baghel RK, Sanodiya BS, Thakur GS, Prasad GB. (2010). "Lentinus edodes: a macrofungus with pharmacological activities". Current Medicinal Chemistry 17 (22): 2419–30. doi:10.2174/092986710791698495. PMID 20491636.
37. Hyodo I, Amano N, Eguchi K. (2005). "Nationwide survey on complementary and alternative medicine in cancer patients in Japan". Journal of Clinical Oncology 23 (12): 2645–54. doi:10.1200/JCO.2005.04.126. PMID 15728227.
38. Mach CM, Fugii H, Wakame K, Smith J. (2008). "Evaluation of active hexose correlated compound hepatic metabolism and potential for drug interactions with chemotherapy agents". Journal of the Society for Integrative Oncology 6 (3): 105–9. PMID 19087767.
39. Shah SK, Walker PA, Moore-Olufemi SD, Sundaresan A, Kulkarni AD, Andrassy RJ. (2011). "An evidence-based review of a Lentinula edodes mushroom extract as complementary therapy in the surgical oncology patient". Journal of Parenteral and Enteral Nutrition 35 (4): 449–58. doi:10.1177/0148607110380684.
40. Terakawa N, Matsui Y, Satoi S. (2008). "Immunological effect of active hexose correlated compound (AHCC) in healthy volunteers: a double-blind, placebo-controlled trial". Nutrition and Cancer 60 (5): 643–51. doi:10.1080/01635580801993280. PMID 18791928.
41. Hérault M, Waton J, Bursztejn AC, Schmutz JL, Barbaud A. (2010). "[Shiitake dermatitis now occurs in France]". Annales de dermatologie et de vénéréologie 137 (4): 290–3. doi:10.1016/j.annder.2010.02.007. PMID 20417363.
42. Hobbs, Christopher and Michael Miovic, eds., Medicinal Mushrooms: An Exploration of Tradtion, Healing and Culture, 2nd ed. (Santa Cruz: Botanical Press, 1995) p.104
43. Kimoto, M., et al., “Effect of Shiitake Mushrooms on Plasma and Liver Lipid Contents in Rats” Eiyo to Shokuryo 29(1976) pp 275-281