Collagen

Bone, marrow, and connective tissue serve as the structural bedrock of the human anatomy, enriched with vital amino acids crucial for physiological well-being. Collagen, a complex protein, is a key component in these tissues. It comprises 19 essential and non-essential amino acids arranged in a triple-helix structure, with each chain containing 1,400 amino acids (Shoulders & Raines, 2009, Annual Review of Biochemistry). Upon exposure to heat, collagen undergoes hydrolysis, transforming into gelatin. This compound boasts a unique amino acid profile, notably rich in hydroxyproline, proline—accounting for 15% of collagen—and glycine, constituting one-third of the collagen protein (Borumand & Sibilla, 2014, Clinical Interventions in Aging). These amino acids are integral for collagen synthesis, and their prevalence in bone broth may offer foundational support for joint, skin, hair, and nail health (Hexsel et al., 2017, Journal of Cosmetic Dermatology). Further rigorous research is warranted for definitive validation of these health benefits (Zdzieblik et al., 2017, Nutrition Research).